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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

上述消息源还称,苹果将在明年10月发布一款12.9英寸的平板电脑,“目标消费群是北美的教育市场(和)……生产商是广达电脑(Quanta Computer)”。有报道称,三星也在研发尺寸在12至13英寸之间的平板电脑,而现在看来,“这些大尺寸平板电脑将极大地影响超极本需求”几乎是板上钉钉的事了。新款“iPad Max”,搭载整合了键盘和电池的新款外壳之后,实际上就是一台笔记本电脑,很有可能在高中生和大学生之中成为主流产品——这一人群需要比现有iPad和iPad Mini产品更好的内容创造工具。
discourse

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

在发达国家低利率和中国对大宗商品旺盛需求助燃下实现的多年增长被认为正在结束,导致国际清算银行(BIS)的经济学家警告,随着借贷成本上升,将会出现负面溢出效应。
Interestingly, a survey found Beijing was thought to be the most congested city in China, among 31.8 percent of respondents, followed by Zhengzhou at 8.8 percent.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 广东质监局将抽检智能洁具产品
Open Access Perspective

Soft matter science and the COVID-19 pandemic

Perhaps my favorite profile this year was Kiki Zhao’s stirring depiction of the remarkable Yu Xiuhua, now one of China’s most read poets, a woman with cerebral palsy who lived most of her 41 years on a farm, writing at a low table. She never finished high school, and says she “could write before she could read.” Now, she is invited to places like Stanford University and fends off comparisons to Emily Dickinson.

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 刘肖:万科不做中年油腻男
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

这份报告还指出,中国现在共有594名以美元计的亿万富翁,这一数字超越了美国的535名,但是并没有一名中国富翁进入全球首富前20名。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

荷兰首相马克?吕特(Mark Rutte)最近由于对安卡拉立场强硬而在民调中排名上升。吕特所属的自由民主人民党(VVD)在民调中略微领先自由党。周二,他将埃尔多安的言论称为“对历史令人恶心的歪曲”,还称“我们不会自甘堕落至这种水平。这完全不可接受”。
The data was released to encourage the adoption of stronger passwords. Mr Slain added:"As always, we hope that with more publicity about how risky it is to use weak passwords, more people will start taking simple steps to protect themselves by using stronger passwords and using different passwords for different websites."
耶路撒冷小女孩参加“圣殿山筛选项目”考古活动时,发现一古埃及护符。
Simply bend one end of the product around yourself or the back of your seat and bend the other end into a secure position for your head. You can even use the hand to hold your device for movie time.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

你有翻白眼的习惯吗?握手时有气无力?不爱进行眼神交流?这些可谓是职业杀手。人们必须意识到行动大于言语,大部分的沟通是通过非语言暗示完成的。你的一些非语言习惯可能会被认为是不礼貌的,不专业的—而这些最终会严重影响你的职业发展。
凯投宏观(Capital Economics)首席亚洲经济学家马克?威廉姆斯(Mark Williams)补充道:“我们预计,2017年新兴市场出口的表现将继续改善,出口值会同比温和增长。”
After all, during the last round of collections, the most striking pieces — from Louis Vuitton, Dior, Proenza Schouler, Narciso Rodriguez — had a streamlined momentum that wasn’t dragged down by any decade-related reference, or identity. They were clothes that went striding into the future, freed from the weight of the past.
“The individual sent an email blast to the entire staff.”

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 美涂士与东易日盛成功联姻
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

['autreid?]

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

有些人仍坚持一种可称为“资源稀缺”的理论。该理论的核心是,资源开发遵循线性模式,低成本的资源最先被开发,也就是说,未来大部分乃至全部开发活动的成本一定会更高。遗憾的是,行业发展历史并不支持这一观点。过去几十年的经验表明,情况正相反。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

draft
adj. 吓人的

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

周一晚间,安卡拉方面证实,不欢迎荷兰驻土耳其大使返回土耳其。
中国中央和地方政府会对技术升级方面投入更多的经费。 包括现代化农业、运输、医疗等方面。这些积极的投资将会进一步提高中国生产和制造业的竞争能力。这将是一次国家行为,目的是为了推动提高产品质量和产品合格率以及以提升产品主导的全球竞争力。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

公司:在线票务平台Eventbrite
I wish you a happy New Year. All affection and best wish

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

单词prime 联想记忆:
Making the cut for the first time, Gigi, 22, and Bella Hadid, 21, are ranked at number five and number nine respectively, with the former making $9.5 million and the younger sibling taking in $6 million.
1.《刺客聂隐娘》(The Assassin)与《疯狂的麦克斯4:狂暴之路》(Mad Max: Fury Road),并列。侯孝贤和乔治·米勒(George Miller)导演了今年最好的两部商业片,二者都应该到你能找到的最大的屏幕上去看。
Inclusive and green finance

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

单词foundation 联想记忆:

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 泛家居行业金融新工具即将面世
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

2. "Breaking Bad" (4.2 million)
Michael Na表示,尽管韩国已经和中国签署了贸易协议,中国政府仍有足够多的其他方式惩罚韩国政府。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“An interviewer walked inta closet instead of the meeting room.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

So ladies, we have been warned. What would your response be?

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

According to the list, ge (哥, older brother, big brother) is without doubt the hottest net word of the year. Both of the top two cited lines use the word. In Chinese, ge here is used more like the first person pronoun (like the English, “Can a brother get a break?”)
Leila Janah
Exports had risen in renminbi terms last month as well, up 5.9 per cent. But when valued in dollars they grew only 0.1 per cent year on year to $196.8bn. Still, that was well above expectations of a 5 per cent fall after contraction had softened somewhat in October to 7.3 per cent.
学习有难度的课程

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

他们在培养核心球员,寻求合适的角色球员。他们可是湖人队啊,对他们而言,很有可能会有一到两个有实力的自由球员主动投怀送抱。
《敦刻尔克》
5.Britons love bleak humour: that's why all the hire bikes are branded with the name of a bank currently being investigated for fixing interest rates. It's supposed to be funny.
莱蒂齐娅·巴塔利亚按时间顺序为当地一家报纸记录了七八十年代巴勒莫的黑手党战争。如今,她的照片被一些博物馆和回顾展收录。
'If global demand picks up in the developed world, and you combine that with the growth in the emerging economies, I think the market is going to get tight,' he said, which means those mighty peaks could return to the oil-price graph.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 2018房改之年: 房价趋稳 房企趋大
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

三、2017年重点工作任务
去年,酷热天气覆盖了阿拉斯加州和大部分美国西部地区。地面温度在所有有人居住的大陆上都创下了记录。科学家说,海洋表面在除南极洲附近海域以外的几乎所有水域中都异常温暖,为造成巨大破坏的太平洋风暴提供了能量。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 听说“共享风”已吹到了家居界?
Critical Review

The role of biosensors in the detection of emerging infectious diseases

慈善组织DoSomething.org本周发布了最慈善明星前20的名单,这位23岁的乡村歌手因给美国国家名人堂博物馆捐款400万美元被授予此称号。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

In an effort to protect China's role in the global economy as a manufacturing hub, the central bank devalued the currency in August, in the biggest drop in decades. Later in the year, after the International Monetary Fund added the renminbi to its group of global reserve currencies, the value of the currency fell further, possibly reflecting capital outflows.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

今年的最佳流行音乐专辑出自几位有许多话要讲的女强人:洛德对孤独的深刻思考,凯莎有关解放的强烈表态;泰勒·斯威夫特就真实的自己与媒体中所呈现的个人形象而与他们算总账。
We will work proactively to expand effective investment.
'The book is true to the character and keeps him as fans would want him, which is as the original hard-bitten guy,' he said.
康涅狄格州斯托宁顿(STONINGTON, CONN.)

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The report notes that China's game developers have been considering subscription models since earlier this year. Among the top 10 games, four are subscription-based titles and two were commercially launched this year, including Shanda Interactive Entertainment Ltd.'s (SNDA) major new title, AION. The Cnzz.com says that a shift to the subscription model would be more likely to create a sense of equity and fairness in the games, because the top players would be those who spend the most time playing, instead of those who spend the most.
2002年,一名4岁的小男孩患有耳聋,但他不愿意戴助听器,因为超级英雄们都不戴。之后,漫威(Marvel)创作了一个戴着助听器的蓝耳侠(Blue Ear)。
n. 飞行,航班
3. You support the teams that I support.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

这项技术曾经运用于武器,但是运用在仿生腿上会更复杂。误读信号可能导致安装者跳下桥或站在开动的车辆前,依靠思想控制的仿生腿需要比武器更为复杂的程序。正如研究者指出的那样:如果你使用仿生胳膊,而胳膊动作做错了,可能只是手肘偏移预订位置。而如果仿生腿动作做错了,那可能就是生命安全问题了。
Scientists confirmed Monday that a skeleton found under a carpark in the English city of Leicester was that of King Richard III, in a bizarre end to a 500-year-old historical mystery.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 宜家又有大动作 进军回收行业!
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Talking to Town & Country, Industry Kitchen Executive Chef Braulio Bunay said he was inspired to create the pizza by the city's Financial District, which he described as 'the epitome of decadence'.
n. 基金;资金,现金(fund的复数) v. 提供资金
Trium跃升3名,击败由凯洛格管理学院(Kellogg School of Management)与香港科技大学(HKUST)联合推出的课程,后者多年来一直高居排行榜榜首。这是Trium首次登上排行榜榜首,也是14年来第四个登上榜首的课程。
根据这份由艾瑞咨询集团与新浪微博联合发布的报告表示,由新浪微博和电信巨头华为联合主办的2016超级红人节高峰论坛在上海举行。
据报道,霍莉·亨特(Holly Hunter)因出演《钢琴课》(The Piano)获最佳女主角奖,她的小金人放在科恩兄弟纽约的办公室中,它旁边还有因出演《冰血暴》(Fargo)而获得的奖杯。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

巴黎排行第三,预计接待游客1803万人。
Mr. Corso restructured Mr. Carell’s nose, giving it a hook. He also shaved his hairline back and gave him more of a forehead.
Wages will finally accelerate after years of stagnation

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Bill Gates topped the list of the world's richest billionaires for the 17th time in 22 years, it has been revealed.
当小李子上台领取奖杯时,制片人哈维韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

'I have to echo that, You have steel in your eyes when you sing. You are totally focused. The first time I heard this song it was fantastic, well this was a step up,’ Simon shared.
随着俄罗斯货币卢布一再对其他货币贬值,近年来去往俄罗斯旅游的旅客也在逐渐增多。
"For IBM, although they regularly top the list of U.S. patentees by volume of patents each year, the Top 100 Global Innovators listing evaluates not just volume, but also success, globalization and impact," said Bob Stembridge, analyst with Thomson Reuters.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

尽管英国商学院的排名平均上升了两位,但法国商学院的排名平均下降了一位——法国是商学院数量最多的欧洲国家。里昂商学院(EMLyon Business School)由于跌出MBA榜单之外,整体排名下降了15位,同时北方高等商学院(Edhec Business School)由于未能进入EMBA榜单,整体排名下降了8位。
据国家质量监督检验检疫总局发言人韩云平称,去年该局对1013批此类商品进行了随机检查--包括玩具、纸尿布、服装和厨具在内的消费品,其中415批商品不合格,占全部抽样产品的40.9%。
adj. 推测的,推理的,思索的,投机的

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

23岁的古纳尔?优素福(Gunal Youssouf)是Teach First人,她加入了普华永道(PwC)英国分公司的管理咨询毕业生项目。优素福表示,在Teach First的两年让她有机会在不用花钱攻读传统资格证书的情况下尝试教学工作。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

7. Viceroy's House

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

但有些人可能就记住了胡子。
n. 学会,学院,协会

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

The studio says it has taken the step because the boy declined to remove a YouTube video he published which promoted how to use the software.
连续4年以来,排行榜前5名的位置都被相同的五个跨洲EMBA项目所占据。Tiemba项目今年能够荣登榜首,不是因为它比竞争对手表现得异常优秀,而是得益于在大多数指标上的强劲表现。尤其是,该项目学员的平均薪资(32.4万美元)排名第二,仅次于凯洛格-香港科大(Kellogg-HKUST)EMBA项目的学员(40.8万美元)。Tiemba项目在职业晋升方面也位居第二,在工作经验方面排名第四。
2.Batman vs Superman: Dawn of Justice
飓风厄玛

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

The Peoria, Ill.-based maker of heavy equipment authorized $10 billion in stock repurchases in January and expected to buy back $1.7 billion of its shares in the first quarter this year to complete its previous $7.5 billion repurchase initiative. The ongoing buybacks are "a result of our record cash flow," said CEO Doug Oberhelman.
Soon after he finished his duties, Sun heard loud voices coming from outside.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

在许多情况下,这种做法已经渐渐从政界边缘进入主流。比如说,英国的执政党保守党立场是中间偏右,它曾经推进英国脱欧,公投之后,新的保守党首相特丽莎?梅(Theresa May)表现出对白人身份政治的同情。
埃玛·莫拉诺一生中唯一的成就可能就是坚持。她活了117岁,并把自己的长寿归功于生鸡蛋和没有丈夫。她于4月15日去世。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

根据荷兰经济政策研究局(Netherlands Bureau for Economic Policy Analysis)发布的《世界贸易监测》(World Trade Monitor)报告,以美元计算,去年跨越国际边境的商品总价值下降了13.8%,是自2009年以来的首次萎缩。这一暴跌很大程度上源于中国和其他新兴经济体的放缓。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 调控加码 楼市“小阳春”难入夏
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

他还贴出了一张自己看着一群种族多元化儿童的图片。
The fall in profits in December highlights the challenges facing an industrial sector racked by overcapacity and falling prices, adding to pressure on authorities to loosen monetary policy and boost infrastructure spending to cushion the slowdown.
In the most significant change in methodology since this ranking was first published in 2005, the FT now collects information about alumni’s first jobs after graduation. These data are used in conjunction with information about their current jobs, three years later. This allows the FT to calculate their salary increase since graduation — a new ranking criterion — as well as their career progress (see methodology).
到了明年3月,这些明日之星中很有可能会有1-2个人脱颖而出,可以成为球队基石。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 建材行业供需格局有望继续好转
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

勇士的横扫,实际上让那些试图挑战勇士的球队无力追赶勇士的脚步,致使联盟在季后赛收入上损失惨重。于是,总决赛便成了战胜勇士的最后的希望,也是最后的机会。总有些愚蠢的人通过不断告诉你不要低估了勒布朗·詹姆斯来让你重燃希望。我看了所有五场詹姆斯在的总决赛,我现在客观的告诉你:詹姆斯知道自己赢不了。“我能做什么?他们赢了73场比赛,我打败了他们,于是他们引进了凯文杜兰特。”在凯文杜兰特用自己的冷血投射杀死系列赛之前,骑士还设法在三场比赛中夺得了一场胜利。但最后,骑士队虽然避免了横扫的尴尬,但他们结束赛季的方式也只能用虎头蛇尾来形容。
到了明年3月,这些明日之星中很有可能会有1-2个人脱颖而出,可以成为球队基石。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

charm(n 吸引力;(女人的)魅力)
3.9 全面加强政府自身建设
contribution

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 楼市调控要推动形成合作博弈
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

fatigue
However, another 876 jobs being offered have not registered a single applicant as of Tuesday, according to Zhonggong. For instance, nobody has so far shown any interest in becoming a railway police officer in Shanghai and Xi'an.
"We'll start with a broad list and then begin to narrow it," Podesta told the Boston Globe. "But there is no question that there will be women on that list."

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

该项调研还显示,会计与金融专业的毕业生也将走俏。那些已在为明年夏天毕业后的生路做打算的学生们需要谨记:上述调研中,有52%的受访雇主表示,他们更愿意雇佣有实习经验的毕业生。
史蒂夫?乔布斯(Steve Jobs)去世后的三年中,维权投资者对苹果发起了攻击,一些人对没有乔布斯的苹果是否还能成功也失去了信心,但现年54岁的库克一直沉着应对。今年,他走出了前任的影子,以自己的一套价值观和议程给苹果公司打上了印记:他引进了新鲜人才,改变了苹果管理巨额现金的方式,扩大了苹果与外部的合作,更加关注社会问题。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

在小说中,格洛搬来与邦德在伦敦同居,并在争吵中一起度过早晨时光。
Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
不过无需置疑,软件的收购同时意味着“人才的收购”,雅虎买下的不只是产品,还有产品背后的人。达洛伊西奥如今已是雅虎伦敦分部的全职员工,而他的青春活力以及无可厚非的独特潜质给这个曾经腐朽老旧的科技巨头注入了迫切需要的新鲜活力。雅虎CEO玛丽莎?梅耶尔赞赏他“力求设计的完美和产品的简约”,并称自己“被他的创造活力和坚韧精神所感染”。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

"绝望主妇"伊娃与老公的性感广告宣传照
2. The new one childplus policy will substantially raise the birth rate, contributing up to 2million new children to the 2014 economy, a 15 percent one-year lift that willonly further boost consumer morale and spirit.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

A new MIT white paper, ominously entitled "Are You Prepared for the Supply Chain Talent Crisis?," bears that out. Supply chain managers need sophisticated tech skills, sure, but they also have to be adept at "high-order diplomacy," expert at general business strategy and problem solving, and able to "thrive in ambiguity," the study says.
时间:2009-10-22 编辑:vicki
反对:可以把这部电影当作一部演技在线的影片,而不是一部真正伟大的作品吗?

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

10月份,中国社会消费品零售总额增长放缓。另一方面,尽管上月出口走弱,中国规模以上工业增加值和全国固定资产投资增长仍大致保持平稳。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 广东:新增绿色建筑9335万平方米
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

我们首先得明白我们所有人都不知道这次选秀会怎么发展,毕竟大学联赛还在进行。但当所有的这些新鲜的血液都齐聚乐透区,这看起来当然美如画。
Developer: Frontier, Microsoft Studios

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

据Bryan Wang说,腾讯跟最近几年在海外特别是新兴市场销量越来越大的那些中国手机厂商达成了预装软件的协议,这给它提供了助力。
We first see the hair of Anna Morales (Jessica Chastain) during the opening credits of “A Most Violent Year.” She’s at her makeup mirror.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

单词tunnel 联想记忆:
朋友很重要

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 进口家具市场混乱 阻碍消费购买
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Facebook的品牌价值增长44%,该公司增加了新的功能,包括平安信使(Safety Check),让用户迅速通知家人和朋友他们是安全的。Elspeth Cheung表示,这些创新提高了这家媒体集团作为一个不可或缺的全球联络媒介的重要性,同时增加了其对广告商的价值。
Movies in 2016 are going to be huge and there's going to be a lot of them. Some of the best movies coming in 2016 include,Batman vs Superman: Dawn of Justice, Captain America: Civil War, Fantastic Beasts and Where to Find Them, Finding Dory, Rogue One: A Star Wars Story, X-Men: Apocalypse, Independence Day: Resurgence, WarCraft and Suicide Squad.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

supply

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Coco
Mr Crabb has taken no exposure to Hong Kong’s property market since setting up in Asia 18 months ago, because he says prices are too high and affordability too low.
The biggest brands outperform financial markets, according to BrandZ, which says this illustrates their financial power and value to shareholders.
谷歌的品牌价值现在超过了1090亿美元,比苹果公司要高大约20亿美元,这使其成为了全世界最赚钱的公司。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

据中国国家通讯社新华社(Xinhua)周四的报道,李克强于周三在柬埔寨召开的一次地区领导人会议上发表讲话称,2017年中国经济发展好于预期,对外贸易扭转了两年来的下滑局面。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Zuckerberg also helped launch a lobbying group that is working toward immigration and education reform in the U.S called FWD.us.
Many believe the population is no longer a major threat to China's resources and environment. Instead, China's population challenges have shifted to low birth rates, an aging society and a widening gender imbalance. China has already experienced a shortage of skilled workers in places like the Pearl River Delta, so it might not be long before we see major reforms.
The annual national civil service exam kicked off last Sunday, and some recent hot topics - such as college graduates starting their own businesses and the Yutu (Jade Rabbit) lunar rover - appeared in the exam questions.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

This is the moment hundreds of lovestruck Irish football fans gathered around a blonde French girl and serenaded her - and one admirer even stole a kiss from the woman at the end.
[praim]

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

As for Dirk, nobody should ever go out the way they do, but it happens all the time. In some ways, maybe it's easier if the reckoning is this painful.
Microscopic as the subjects are, the benefits of the scientists’ research are set to be huge.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 10月建材家居销量普涨但低于预期
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

上周五,中国汽车制造协会宣布,1月份的乘用车销量达到220万台,比去年同期增长了9.3%,同时,新能源汽车的产量则激增了144%。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

这个所谓的“百万富翁的游乐场”现已向所有人敞开怀抱。经济型的酒店、家庭旅馆以及带有自助厨房的公寓,都使得塞舌尔之行不再价格高昂。塞舌尔由100多个散布在印度洋上的岛屿组成,这里有多种多样的娱乐活动供您选择,诸如沙滩浴、钓鱼、潜水、航海和乘船游览。塞舌尔群岛一年四季的热带气候可谓得天独厚,所以你随时都可以开始你的塞舌尔之行。
This year they looked at the use of negative strategies such as anger or stonewalling responses to conflict, and found that these predicted health-related changes over time in specific ways.
上榜理由:被低估的欧洲瑰宝

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

?奥巴马总统在纽约和新泽西宣布一场“大灾难”。洪水摧毁了海岸和超过230万人失去了电。在新泽西国家警卫队从洪水中救出数百人。州长克里斯?克里斯蒂,共和党人,说这次损失是“无法想象的”。他赞扬了从奥巴马那收到的“突出”配合。
['benifit]
No. Having ended Robert Mugabe’s 37-year rule — with a little help from the army — Emmerson Mnangagwa has promised free elections in 2018. That raises one problem: he could lose. He must at least pretend elections are fair because he needs donor money to help turn the economy around. That would mean electoral reforms, which risk a loss for his unpopular Zanu-PF. Even if Mr Mnangagwa were prepared to roll the electoral dice, it is not clear the army is. Having got their man in, Zimbabwe’s generals are unlikely to allow the public to kick him out.
纸筒插秧机

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 家居电商化须探“特色”之路
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The data was released to encourage the adoption of stronger passwords. Mr Slain added:"As always, we hope that with more publicity about how risky it is to use weak passwords, more people will start taking simple steps to protect themselves by using stronger passwords and using different passwords for different websites."
[.di:m?'gr?fik]

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

6. Bubloon
A jailed con artist who falls in love with another inmate and escapes prison multiple times could only be the work of fiction, but this is more or less the real story of Steven Jay Russel. Much like his film counterpart, played by Jim Carrey, Russell was originally sent to prison for fraud. He escaped his first sentence to be with his partner Jim Kemple, who at the time was dying from AIDS. Russell was found two years later and returned to prison. Kemple died soon after.
Libby has posted the lyrics on her YouTube channel in the comments section, but here they are for you. There are plenty of lovely English expressions and British English slang that I’ve highlighted in bold for you. Can you guess the meaning? What does “OMG” stand for?

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 楼市调控加码 销售投资趋冷
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China purchased 141,000 industrial robots in 2017, up 58.1% year-on-year, but foreign brands accounted for nearly three quarters of that, showing that the gap is still widening between Chinese robot makers and their foreign peers.
不过,我们大部分人都有自知之明,在粉饰过去的同时就已意识到自己是在自欺欺人。我们知道这种倾向在政治界的危害(看看布什和克林顿吧)。可是,在时尚界又何尝不是如此呢?

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